Research Article

A New Validated Stability Indicating RP-HPLC Method for Simultaneous Estimation of Pyridoxine Hydrochloride and Meclizine Hydrochloride in Pharmaceutical Solid Dosage Forms

Table 4

Accuracy studies of PYH and MEH in drug-matrix solutions.

Amount added
(mg mL−1)
Peak area
Amount recovered
(mg mL−1)
% Recovery% Recovery
(mean ±  %RSD)
Over all
(mean ±  %RSD)

PYH0.39528045050.39299.24
0.39528053010.402101.65
0.39528046700.402101.65
0.49434816890.497100.71
0.49434874330.495100.20
0.49434850390.498100.81
0.59241819050.595100.51
0.59241815070.59099.66
0.59241834550.58398.48

MEH0.20310846740.207101.88
0.20310843500.206101.64
0.20310859470.207101.88
0.25213458090.253100.38
0.25213425890.25299.81
0.25213483490.25299.81
0.30416245890.308101.41
0.30416234700.308101.25
0.30416253470.30299.22