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Chromatography Research International
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Special Issues
Chromatography Research International
/
2013
/
Article
/
Tab 7
/
Research Article
A New Validated Stability Indicating RP-HPLC Method for Simultaneous Estimation of Pyridoxine Hydrochloride and Meclizine Hydrochloride in Pharmaceutical Solid Dosage Forms
Table 7
Ruggedness of the method.
Amount of PYH (mg tab
−1
)
Amount of MEH (mg tab
−1
)
Analyst 1, instrument 1, column 1
Analyst 2, instrument 2, column 2
Amount found PYH (mg tab
−1
) (Mean ± %RSD)*
Amount found MEH (mg tab
−1
) (Mean ± %RSD)*
Amount found PYH (mg tab
−1
) (Mean ± %RSD)*
Amount found MEH (mg tab
−1
) (Mean ± %RSD)*
50
25
50.53 ± 0.3
25.63 ± 0.3
50.97 ± 0.04
25.60 ± 0.50
Mean of six replicates.