A Validated New Gradient Stability-Indicating LC Method for the Analysis of Doripenem in Bulk and Injection Formulation

Table 2

Peak purity results of forced degradation studies of drug product.

Stress condition	% Degradation	Purity angle	Purity threshold	Purity flag
Acid stress	24.0	0.549	1.638	No
Base stress	18.3	0.604	1.710	No
Oxidation stress	23.1	0.566	1.706	No
Water stress	9.7	0.783	2.461	No
Photolytic stress	0.0	0.841	3.165	No
Heat stress	0.3	0.874	3.224	No
Humidity stress	0.2	1.066	3.068	No