A Case of Sublingual Ranula That Responded Successfully to Localized Injection Treatment with OK-432 after Healing from Drug Induced Hypersensitivity Syndrome

Figure 4

Procedure of first local injection of OK-432 solution (0.7 KE/0.3 mL) using a 27-G needle (a). The cyst showed no inflammation after the first procedure. Nine consecutive days later, we punctured the cyst using an 18 G needle, and the maximum possible amount of mucus (10 mL) was aspirated immediately (b). OK-432 solution (0.2 Klinische Einheit [KE] per millimeter; total 1 KE/5 mL) was then injected using the same needle (c). There was mild spontaneous pain and swelling with redness around the injected region over the center-line of the mouse at eight days after the second injection of OK432 (1 KE/5 mL) (d).

(a)

(b)

(c)

(d)