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Case Reports in Dermatological Medicine
Volume 2012 (2012), Article ID 612434, 4 pages
http://dx.doi.org/10.1155/2012/612434
Case Report

Panniculitis Is an Important Feature of Cutaneous Leishmaniasis Pathology

1Scientific Council of Dermatology & Venereology, Iraqi Board for Medical Specializations, Baghdad 12114, Iraq
2Iraqi Society of Dermatology & Venereology, Medical Collection Post Office, P.O. Box 61080, Baghdad 12114, Iraq
3Department of Dermatology, College of Medicine, Baghdad University, Baghdad, Iraq

Received 15 January 2012; Accepted 10 February 2012

Academic Editors: T. Erdem, S. Kawara, and E. Schmidt

Copyright © 2012 Khalifa E. Sharquie and Ammar Faisal Hameed. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Cutaneous leishmaniasis is an inflammatory parasitic infection characterized by superficial and deep perivascular infiltration with or without granuloma formation. Clinical diagnosis usually requires seeing Leishmania bodies. Methods. We report two cases of cutaneous leishmaniasis with unusual histological finding of panniculitis. Case 1: a 36-year-old male presented with multiple ulcerative nodules involving the left leg for two months duration which was greatly responsive to antimony intralesional therapy. Case 2: A 45-year-old woman presented with painless nodules on her upper chest of a 10-week duration which were successfully treated with oral and topical zinc sulphate. Results. Diagnosis of both cases was confirmed by finding the Leishmania bodies with Gimesa stain in addition to the diffuse dermal inflammatory cellular infiltration of the dermis forming granulomatous dermatitis. Mixed cellular infiltration of lymphocytes, histiocytes, and plasma cells of the panniculus caused both septal and lobular panniculitis. Conclusion. Cutaneous leishmaniasis can cause panniculitis and this could be seen more commonly if deep biopsies were taken. So cutaneous leishmaniasis must be considered in evaluating pathology of panniculitis especially in endemic regions.