|
Common findings in published cases of bullosis diabeticorum | Our case |
|
Long-standing diabetes mellitus | Yes |
Blisters occur spontaneously and abruptly, usually without known antecedent trauma | Yes |
Lesions tend to be asymptomatic, despite mild discomfort or burning | Lesions were pruritic |
Associated with neuropathy | No neuropathy |
Blisters heal spontaneously within 2–6 weeks of onset | Lesion took more time to heal and were more persistent |
Tense blisters | Yes |
Evolve on nonerythematous or normal appearing skin | Lesions erupted on erythematous base |
Mild or no scarring | Yes, depressed thin scars |
Blisters typically occur on the feet or lower legs | Yes |
Blisters tend to be large, size ranging from few millimetres to several centimetres | 3–7 mm with no tendency to coalesce |
Negative immunofluorescence: no primary immunologic abnormality exists | Yes |
The blister plane may appear in a subcorneal, intraepidermal, or subepidermal location | Yes, blisters were intrepidermal |
Presence of degenerative and necrotic keratinocytic | Yes |
Absence of urinary uroporphyrins | Yes |
Recurrence of condition is common | Yes |
More in males | Our case was a female |
|