Case Report
Methylprednisolone Therapy in Acute Hemorrhagic Edema of Infancy
Table 1
Clinical differences between acute hemorrhagic edema of infancy (AHEI) and Henoch-Schönleins purpura (HSP).
| Clinical findings | AHEI | HSP |
| Peak incidence | 4 to 24 months | 4 to 7 years | Skin distribution |
Faces, auricles, and extremities | Extensor surfaces of the legs and buttocks | Edema | Consistent, nonpitting | Inconsistent | Gastrointestinal involvement | Rare | Common | Articular involvement | Rare | Common | Renal involvement | Extremely rare | Common | Skin histology | Leukocytoclastic vasculitis, frequently with fibrinoid necrosis | Leukocytoclastic vasculitis | Perivascular deposits | C1q | IgA | Duration | 2-3 weeks | 1 month or more | Relapses | Rare | Frequent |
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