Hypothyroidism Complicating Nephropathy in a Diabetes Patient

Table 1

Investigations at different time points.

	−4.5 months	0 time	+1 month	+4 months	Reference
Serum TSH	—	160	09	04	0.27–4.2 mIU/L
TPO antibody	—	>500	—	—	<40 IU/L
Total cholesterol	381	220	254	259	<200 mg%
Triglyceride	1286	250	619	280	<150 mg%
LDL	—	119	—	148	<100 mg%
HDL	16	51	26	55	>40 mg%
HbA1c	6.7%	7.2%	—	—	6%-7%
Serum creatinine	1.5	1.6	1.1	1.1	0.6–1.2 mg%
*MDRD eGFR	55	51	79	79	≥90 mL/min per 1.73 m^2
Serum CPK	—	2810	104	—	25–200 IU/L
Serum LDH	—	549	378	—	225–420 IU/L
Serum SGOT	—	201	15	—	<37 IU/L
Serum SGPT	—	66	—	—	<65 IU/L
Serum K^+	—	5.5	4.4	4.3	3.5–5 meq/L
Serum albumin	—	4.2	4.2	4.0	4-5 gm%
Urine protein/creatinine ratio	—	1.6	1.0	1.0	<0.3
Urine microscopy	—	4-5 pus cells/HPF	8–10 pus cells/HPF	4–6 pus cells/HPF	0–2 pus cell/HPF
Urine C/S	—	Sterile	Sterile	—	Sterile

*MDRD eGFR: Modification of diet in renal disease estimated glomerular filtration rate.