Case Report
Syndrome of Inappropriate Antidiuretic Hormone Secretion and Ibuprofen, a Rare Association to Be Considered: Role of Tolvaptan
Table 1
Published cases of NSAID-induced SIADH.
| Authors | Reference | No. of pts. | Initial sodium levels (mmol/L) | Therapy | Drug involved |
| Temple et al. | [13] | 2 | 131–134 | Mannitol/fluid restriction | Salicylate | Blum and Aviram | [14] | 1 | 115 | Fluid restriction | Ibuprofen | Dunn et al. | [15] | 2 | 118 118 | Fluid restriction Fluid restriction | Ibuprofen Diclofenac | Petersson et al. | [16] | 2 | 119 120 | Hypertonic saline Isotonic saline/fluid restriction | Piroxicam Diclofenac | Cheung et al. | [17] | 1 | 116 | Fluid restriction | Nabumetone/diclofenac | Rault | [18] | 1 | 125 | Isotonic saline | Ibuprofen | Shimada et al. | [19] | 1 (twice) | 118 104 | Fluid restriction | Metamizole Propyphenazone |
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