Case Report
Tumor-Induced Osteomalacia: Increased Level of FGF-23 in a Patient with a Phosphaturic Mesenchymal Tumor at the Tibia Expressing Periostin
Table 1
Laboratory data of the patient before and after resection of the giant cell tumor.
| Laboratory value (normal range) | Before resection | 2 days after resection | 2 months after resection | 26 months after resection | 29 months after resection | Last follow-up, 34 months after resection |
| FGF-23 c-terminal (0.026–0.110 RU/mL or 20–70 pg/mL | 0.396 (+) | 0.037 (normal) | Normal | Normal | Normal | Normal | Phosphate (2.6–4.5 mg/dL) | 1.95 (−) | n.p. | Normal | Normal | 2.14 (−) | Normal | Calcium (8.5–10.1 mg/dL) | Normal | Normal | Normal | Normal | Normal | Normal | Alkaline phosphatase (40–129 U/L) | 305 U/L | 276 U/L | 178 U/L | Normal | Normal | Normal | Bone specific alkaline phosphatase (<75%) | 79.6% | n.p. | n.p. | n.p. | Normal | Normal | 1.25-(OH)2D (16–81 pg/mL) | 4.83 (−) | n.p. | Normal | Normal | Normal | Normal | 25-(OH)-D (20–60 ng/mL) | 21 (normal) | n.p. | 17.3 (−) | Normal | Normal | Normal | Parathyroid hormone (15–65 ng/L) | Normal | Normal | Normal | Normal | Normal | Normal |
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n.p. = not performed.
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