Temozolomide-Induced Shrinkage of Invasive Pituitary Adenoma in Patient with Nelson’s Syndrome: A Case Report and Review of the Literature

Table 1

Laboratory tests in patient at the moment of diagnosing Cushing’s syndrome.

Diagnostic test	Normal; range	Patient result
ACTH (pg/mL) 8.00 am	<46.0	81.0
Cortisol (μg/dL) 8.00 am	4.3–22.4	54.45
Cortisol (μg/dL) 6.00 pm	3.09–16.66	52.72
Urinary excretion of cortisol/24 h (μg/dL)	32–243	825.6; 1275.5
Cortisol (μg/dL) after 8 mg DXM suppression test	↓50%	54.45 → 41.2; ↓24%

According to local laboratory 2006.