A Rapid Biochemical and Radiological Response to the Concomitant Therapy with Temozolomide and Radiotherapy in an Aggressive ACTH Pituitary Adenoma

Figure 2

(a) HE staining of the pituitary macroadenoma tissue confirming atypical pituitary adenoma (magnification 100). (b) Ki-67 positivity in tumor tissue of 10–20% (magnification 400). (c) p53 positivity in less than 5% of cells (magnification 400).

(a)

(b)

(c)