Clinical Findings Associated with a De Novo Partial Trisomy 10p11.22p15.3 and Monosomy 7p22.3 Detected by Chromosomal Microarray Analysis

Table 1

Phenotypic findings in our patient and patients reported in the literature with either pure trisomy 10p11.2p15.3 or monosomy 7p22.

Name/case	Present case	Schleiermacher et al. [1] ^a	Granata et al. [2]	Schomig-Spingler et al. [3]
Gender	Male	Male+ Female	Mixed	Mixed
Genotype	10p+, 7p−	10p+	10p+	7p−
Growth retardation	+	+	9/9	ND
High-arched palate	+	+	7/9	7/12
Wide fontanelle(s)	+	+	6/9	ND
Hypertelorism	+	ND	5/9	2/12^b
Micrognathia	+	ND	5/9	ND
Feet anomaly	+	+	4/9	6/12
Thrombocytopenia	+	ND	1/9	ND
Posterior ear rotation	+	+	ND	1/12
Detection method	aCGH	Karyotype	Karyotype	Karyotype

^aThis paper describes the first case of 10p trisomy, with the same breakpoints as in our patient’s case.
^bThe patients were reported to have either hyper- or hypotelorism.
ND: not described.