640563.fig.004a
(a)
640563.fig.004b
(b)
640563.fig.004c
(c)
640563.fig.004d
(d)
Figure 4: FISH of metaphase spread with the Vysis Telvysion probe, which hybridizes the Xp and Xq telomeres signals (a) and (c) shows Xp and Xq telomere signals on 45, XO metaphase spread, whereas (b) and (d) show Xp and Xq signals on normal chromosome X, and loss of Xp and Xq on 46,X+ringX metaphase spread.