Detection of Chromosome X;18 Breakpoints and Translocation of the Xq22.3;18q23 Regions Resulting in Variable Fertility Phenotypes

Figure 1

Pedigree. *Affected individual detected. B: balanced translocation detected; 46, X, t(X;18)(q22.3;q23). U: Unbalanced translocation detected; 46, X, der(X), t(X;18)(q22.3;q23). D: donor—individual 2 : 4 carried pregnancy 3 : 4 using donor egg (from individual 2 : 5) and partner’s sperm (from individual 2 : 3). P: Pregnancy resulted from donor egg (from individual 2 : 5). SAB: spontaneous abortion (individual 3 : 3). NAD: no abnormalities detected.