Case Report
Detection of Chromosome X;18 Breakpoints and Translocation of the Xq22.3;18q23 Regions Resulting in Variable Fertility Phenotypes
Table 1
Theoretical meiotic segregation patterns for translocation: 46, X, t(X;18)(q22.3;q23).
| Segregation type | Cell 1 | Cell 2 |
| Alternate (result is balanced or normal)a | X + 18 | der(X) + der(18) | Adjacent 1b | X + der(18) | der(X) + 18 | Adjacent 2b | X + der(X) | 18 + der(18) | Tertiary trisomyb | X + 18 + der(X) | der(18) | Tertiary trisomyb | X + 18 + der(18) | der(X) | Interchange trisomyb | der(X) + der(18) + X | 18 | Interchange trisomyb | der(X) + der(18) + 18 | X | 4 : 0b | X + der(X) + 18 + der(18) | — |
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aNormal or balanced meiotic segregation pattern.
bAbnormal theoretical meiotic segregation pattern.
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