A Newborn with Panhypopituitarism and Seizures

Table 1

Clinical features in patients with panhypopituitarism and interstitial deletions of 20p11 overlapping regions.

Characteristic traits	Present study	Williams et al., 2011 [5]	Garcia-Heras et al., 2005 [6]	Kamath et al., 2009 [4], case # 20
Chromosomal deletion	20p11.21p12.1	20p11.21p11.23	20p11.1p12	20p11.1p12.2
Gender	Female	Female	Male	Male
Panhypopituitarism	+	+	+	+
Cognitive delay	+	+	NS	+
Congenital heart disease	+	+	−	−
Gastrointestinal system anomalies	+	+	NS	−
Genitourinary system anomalies	+	NS	+	−
Hypoglycemia	+	NS	+	NS
Abnormal brain imaging study	+	+	+	+
Seizures	+	+	NS	NS
Flat nasal bridge	+	+	+	−
Cleft lip/palate	−	+	−	NS
Retrognathia	+	−	+	NS
Low set ears	+	+	NS	NS
Preauricular pits	−	+	+	NS
Vertebral defects	−	+	−	−

NS: not specified.