Epigenetic Alterations in a Gastric Leiomyoma

Table 2

List of methylated genes in the gastric leiomyoma studied. Gene names and gene symbols are according to the HGNC database; CpG site locations are mentioned based on the MRC-Holland data sheets. TP indicates tumor periphery and TC tumor center.

Gene symbol	Name	CpG location	Sample	Mehtylation %
APC	Adenomatous polyposis coli	21 nt before TSS	TP	27.7
			TC	0
MGMT	O-6-Methylguanine-DNA Methyltransferase	233 nt after TSS	TP	9.5
			TC	0
MSH6	mutS homolog 6	317 nt before TSS	TP	14.3
			TC	0
MLH1	MutL Homolog 1	382 nt before TSS	TP	77.6
			TC	59.2
MSH3	mutS homolog 3	485 nt before TSS	TP	10.8
			TC	11.6

TSS: transcription start site. nt: nucleotide.