Case Report

Metastatic Renal Cell Cancer to Thyroid Diagnosed by Endoscopic Ultrasound Guided Fine Needle Aspiration Technique

Figure 2

(a) Cell block of thyroid nodule FNA is displaying multiple nests of clear cells, which have clear to eosinophilic cytoplasm. These nests are separated by delicate vascular network and surrounded by lymphocytic infiltrate (hematoxylin-eosin stain, original magnification ×400). (b) Staining of cell block with PAX-8 shows strong nuclear positivity (PAX-8 immunohistochemistry stain, original magnification ×200). (c) Staining the cell block with thyroid transcription factor-1 (TTF-1) shows negative staining (TTF-1 immunohistochemistry stain, original magnification ×200). (d) Kidney section is showing multiple nests of clear cells, which have clear to eosinophilic cytoplasm. These nests are separated by delicate vascular network (hematoxylin-eosin stain, original magnification ×400).
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