Table 1: Comparison of published reports of plasma cell myeloma (or multiple myeloma) with thyroid cartilage involvement.

AuthorsDemographicsInitial diagnosis of multiple myelomaPresentation of thyroid cartilage lesionImagingSkeletal survey at time of presenting thyroid lesionTreatment of thyroid lesion

Van Dyke C et al. [3]62-year-old maleExpansile lytic rib lesionWorsening hoarseness for 6 months and neck swelling for weeksContrast-enhanced CTMultiple bony lesions on radiographic surveyRadiation therapy
Saad R et al. [4]79-year-old maleOsteolytic lesion of 6th thoracic vertebraNeck mass associated with pain upon swallowingContrast-enhanced CTMultiple lytic bony lesions on radiographic surveyNot reported
Gross M et al. [5]50-year-old maleNeck massProgressively enlarging neck mass for 6 months with respiratory distress and stridorNon-contrast CTMultiple lytic bony lesions on radiographic surveyRadiation and chemotherapy (vincristine, doxorubicin, and dexamethasone; later changed to melphalan)
Aslan I et al. [1]70-year-old maleNeck massSlight hoarseness and neck fullness for 4 monthsNon-contrast CTNo lesions demonstratedDebulking of mass and radiation therapy
Sosna J et al. [6]54-year-old maleNeck massRecent neck lump detected by patient with increasing hoarseness and progressive dyspneaNon-contrast CTMultiple lytic bone lesions on radiographic surveyRadiation and chemotherapy (vincristine, doxorubicin, and dexamethasone; later given melphalan)
Shimada T et al. [2]72-year-old malePathologic cervical vertebral body fractureAsymptomatic, incidentally discovered on CT of cervical spineNon-contrast CTNo additional lesions on whole body scintigraphyChemotherapy and/or bone marrow transplant felt indicated, but no therapy given, due to patient’s age and dementia.
Kalina P et al. [7]60-year-old maleNasolacrimal duct obstruction with epiphoria due to paranasal sinus massHoarseness for 3 monthsContrast-enhanced MRI; contrast-enhanced CT, and bone scanTwo lytic lesions, one each of the skull and left humerusAutologous bone marrow transplant