Acute Myeloid Leukemia Evolving from JAK 2-Positive Primary Myelofibrosis and Concomitant CD5-Negative Mantle Cell Lymphoma: A Case Report and Review of the Literature
Figure 3
Acute myeloid leukemia and associated bone marrow involvement by mantle cell lymphoma: (a) peripheral blood smear, Wright-Giemsa stain, blasts, Ob. 100x, immersion oil. (b) Bone marrow biopsy, Ob. 20x, anti-CD34 antibody highlights positive blasts; the lymphoid cells are negative. (c) Bone marrow biopsy, hematoxylin and eosin stain, Ob. 50x, lymphoid aggregate and blasts. (d) Bone marrow biopsy, anti-CD20 antibody highlights a large subset of positive cells in a lymphoid aggregate, Ob. 20x. (e) Bone marrow biopsy, anti-CD3 antibody highlights a small subset of positive cells in a lymphoid aggregate, Ob. 20x. (f) Bone marrow biopsy, anti-Cyclin D1 antibody highlights a large subset of positive cells in a lymphoid aggregate, Ob. 20x.
