Biclonal IgD and IgM Plasma Cell Myeloma: A Report of Two Cases and a Literature Review
Figure 2
Case 2. (a) Bone marrow aspirate reveals large numbers of mature-appearing plasma cells with lymphoplasmacytoid morphology, some of which contain Dutcher bodies and cytoplasmic immunoglobulin inclusions. (b) Immunohistochemical studies on the trephine biopsy demonstrate that almost all cells express IgM, some with Dutcher bodies. (c) A subset of cells also express IgD but at a weaker intensity than those expressing IgM. Wright-Giemsa, original magnification ×1000 (a); IgM, original magnification ×500 (b); IgD, original magnification ×500 (c).
