An Acquired Factor VIII Inhibitor in a Patient with HIV and HCV: A Case Presentation and Literature Review

Table 1

Comparison between a meta-analysis by Delgado et al. [33], a case series by Collins et al. [2], and our patient.

Characteristics	Delgado et al. [33] (2003)	Collins et al. [2] (2007)	Our patient (2013)
Number of patients	249	154	1
Age category (median)	64 (range, 8–93)	78 (range, 2–98)	57
Sex	Female: 55%	Female: 57.38	Male
Underlying diagnosis	Malignancy; Postpartum status; Autoimmune disorders	None: 63.3%; Autoimmune or collagen vascular disease: 16.7%; Malignancy: 14.7	HCV, HIV, LA, MGUS
FVIII level category at diagnosis (median)	2 IU/dL (range, 0–30)	4 IU/dL (range, <1–12 IU/dL)	<1 IU/dL
Inhibitor titer at diagnosis (median)	10.0 BU/mL (range, 0.9–32,000)	7.2 BU/mL (range, 1.4–219 BU/mL)	230.4 BU/mL