Perioperative Management of Type 2N Von Willebrand’s Disease with Recombinant Factor VIII in a Patient Undergoing Knee-Replacement Surgery

Table 1

Perioperative APTT and FVIII levels.

	Baseline	After 30 min RFVIII (2000U)	1 hr later	6 hrs after	D + 1	D + 2	D + 3
APTT (22–34 sec)	48.1	38.6	38.5	38.1	37.9	40.7	40.2
FVIII (40–200 IU/dL)	66.3	118.1	138.3	110.7	98	108.9	163.4

D + (number): (number) of days after surgery.