Case Report
Cerebral Sinus Venous Thrombosis due to Asparaginase Therapy
Table 1
Laboratory parameters 3 weeks after PEG-Asparginase therapy.
| Laboratory parameters | Reference ranges | Patient results |
| PT/INR | 10.1–13.6 seconds/0.9–1.2 | 18.7/1.7 seconds | aPTT | 24–36 seconds | 39 seconds | D-Dimer | 0–0.5 mg/L | 1.67 mg/L | Fibrinogen | 1.5–4 g/L | 0.6 g/L | Factor VIII activity | 0.5–2 IU/mL | >2 IU/mL | Protein C function | 0.5–1.24 IU/mL | 0.77 IU/mL | Protein S (total/free) | 0.52–0.99/0.51–1.18 IU/mL | 0.65/0.52 IU/mL | AT-III assay | 70%–110% | 93% | Anticardiolipin | | | IgG | <10 GPL/mL | 8 GPL/mL | IgA | <7 APL/mL | <2 APL/mL | IgM | <7 MPL/mL | <3 MPL/mL | Homocysteine | 5–15 µmol/L | 3 µmol/L | Fasting lipid profile | | | Total cholesterol | 0–5 mmol/L | 3.9 mmol/L | Triglyceride | 0–2.3 mmol/L | 1.3 mmol/L | HDL | 1–1.5 mmol/L | 1.4 mmol/L | LDL | 0–2.5 mmol/L | 2.2 mmol/L |
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PT: prothrombin time, aPTT: activated partial thromboplastin time.
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