|
| Case | Age/sex | Symptoms | Cycles of AZA | Initiation of symptoms
(days) | Radiographic findings | Lung pathology | CRP
(mg/dL) | MDS WHO 2008
classification | Cytogenetic | R-IPSS | ANC
(cells/L) | ALC
(cells/L) | Platelet count
(/L) | Ref. |
|
| 1 | 72/M | Fever, shortness of breath | 1 | 3 | Interstitial pneumonitis, ground-glass opacities | NA | 10.2 | RAEB-1 | 46, XY, der(1;7)(q10;p1) [17/20] | Very high | 90 | 540 | 18000 | [3] |
|
| 2 | 64/M | Dry cough, fever, and chills | 2 | 2 | Left lower lobe infiltrate | Fibrinous and organizing pneumonia | NA | t-MDS | NA | NA | 140 | 490 | 12000 | [4] |
|
| 3 | 74/M | Dry cough, shortness of breath | 1 | 7 | Nonsegmental consolidation/ground-glass opacities | NA | 1.25 | RAEB-1 | Complex | Very high | 630 | 1790 | 17000 | [5] |
|
| 4 | 56/M | Dry cough, fever | 1 | 2 | Nodular opacities, bilateral airspace disease | Interstitial lung disease, organizing pneumonia with bronchocentric granulomatous pattern | NA | RAEB-2 | NA | NA | 750 | NA | 12000 | [6] |
|
| 5 | 71/M | Fever, shortness of breath | 1 | 14 | Diffuse bilateral interstitial/alveolar infiltrates | Focal areas of intra-alveolar acute inflammation and necrosis | NA | NA | NA | NA | NA | NA | NA | [7] |
|
| 6 | 74/F | Fever, dry cough, and shortness of breath | 2 | 5 | Reticulonodular and ground-glass shadowing and small pleural effusions | NA | NA | NA | Complex | Very high | 4300 | NA | 342000 | [8] |
|
| 7 | Case | Shortness of breath | 11 | 330 | Bilateral interstitial lung infiltrates | NA | 0.68 | MDS derived AML | Complex | Very high | 1750 | 1250 | 579000 | Case |
|
