Heparin-Induced Thrombocytopenia in a Patient with Essential Thrombocythemia: A Case Based Update

Table 2

Case number	Hematologic disorder	Age/sex	Disease treated with heparin	Initial platelet count × 10^9/UL	Platelet nadir × 10^9/UL	New thrombotic event	Coagulation disorder/organ failure	Fibrinogen degradation product	Author/year
1	ET	52/F	Cranial sinus thrombosis	1008	109	None	None	No evidence of DIC	Walther et al. (1996) [15]
2	ET	57/M	Transient ischemic attack	1235	633	None	None	Not described	Risch et al. (2000) [11]
3	ET	78/F	Subclavian and axillary thrombosis	965	194	None	None	Not described	Houston (2000) [10]
4	ET	45/F	Mesenteric and portal vein thrombosis	840	110	Femoral vein thrombosis and subclavian venous thrombosis	None	Not described	Spectre et al. (2008) [16]
5	ET	71/F	Spleen infarction	640	383	Heparin-induced skin necrosis	None	Not described	Spectre et al. (2008) [16]
6	ET	38/F	Budd-Chiari syndrome	175	78	Pulmonary embolism	Not described	Not described	Randi et al. (2010) [17]
7	ET	66/F	DVT and pulmonary embolism	700	6	Not described	Not described	Not described	Lapecorella et al. (2010) [12]
8	ET	61/F	Cerebral venous thrombosis	517	42	Extension of cerebral venous thrombosis	None	Not described	Richard et al. (2011) [13]
9	ET	67/F	Cerebral infarction	1270	7	Cerebral infarct, femoral artery occlusion, and thrombophlebitis of extremities	Dyspnea, petechiae, and hematuria	Increased by 20–30 µL	Murawaki et al. (2012) [9]
Present case	ET	67/F	NSTEMI	750	216	Cerebral infarct, popliteal vein thrombosis	Acute renal failure	No evidence of DIC	Present