Morphological Transformation of Myeloma Cells into Multilobated Plasma Cell Nuclei within 7 Days in a Case of Secondary Plasma Cell Leukemia That Finally Transformed as Anaplastic Myeloma

<div>Morphological changes in myeloma cells two months after the development of secondary plasma cell leukemia. The diameter of the myeloma cells in the bone marrow significantly enlarged by approximately twofold, and pleomorphic nuclei and vacuoles in the cytoplasm were observed, indicating a transformation into anaplastic myeloma (1,000x, May–Grünwald-Giemsa staining).</div>

Case Reports in Hematology

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Figure 3: Morphological Transformation of Myeloma Cells into Multilobated Plasma Cell Nuclei within 7 Days in a Case of Secondary Plasma Cell Leukemia That Finally Transformed as Anaplastic Myeloma 

Figure 3 | Morphological Transformation of Myeloma Cells into Multilobated Plasma Cell Nuclei within 7 Days in a Case of Secondary Plasma Cell Leukemia That Finally Transformed as Anaplastic Myeloma 