Case Report

A Case of Myeloproliferative Neoplasm with BCR-FGFR1 Rearrangement: Favorable Outcome after Haploidentical Allogeneic Transplantation

Table 1

Characteristics of 12 patients with BCR-FGFR1 rearrangement treated with allo-HSTCT.

CaseReferenceAge (years)/sexDiagnosisDonor sourceResponse

1Present report65/MMPNHaploidentical HSCTCCyR
2Konishi et al., 2018 [8]48/MB-ALL/MPNMismatched unrelated, BMCCyR
3Montenegro et al., 2017 [3]41/FB-ALL/MPNNRResidual disease
4Wang et al., 2016 [9]56/FB-ALL/MPNMatched unrelated AHSCTRemission for 5 months after AHSCT
5Landberg et al., 2017 [10]21/MMPNMismatched unrelated AHSCTRemission for 4 years after AHSCT
6Khodadoust et al., 2015 [11]47/MTrilineage mixed-phenotype ALMatched sibling allogeneic HSCTResidual disease
7Shimanuki et al., 2013 [12]58/FAL with dysplasiaMatched sibling allogeneic HSCTResidual disease and subsequent relapse
8Morishige et al., 2013 [7]50/MTrilineage AL/lymphomaCord bloodRemission for 2 years after AHSCT
9Dolan et al., 2012 [6]8/MMDS/MPNUnrelated AHSCTRemission for 4.5 years after AHSCT
10Haslam et al., 2012 [13]21/MB-ALL/MPNMismatched, unrelated AHSCTResidual disease
11Kim et al., 2011 [14]59/MMyeloid, T cellAHSCTCCyR
12Patnaik et al., 2010 [15]57/FMPNAHSCTRemission for 42 months after AHSCT

Abbreviations: M: male; F: female; MPN: myeloproiferative neoplasm; B-ALL: B-cell acute lymphoblastic leukaemia; CCyR: complete cytogenetic response; AL: acute leukaemia; MDS: myelodysplastic syndrome; AHSCT: allogeneic hematopoietic stem-cell transplantation; BM: bone marrow; NR: Not reported.