Granulomatous Hepatitis Secondary to Histoplasma Infection after Treatment with Infliximab

Figure 1

(a) HE ×20, presenting two granulomas (arrows) and (b) HE ×40, showing inflammatory infiltrate and clusters forming numerous microabscesses, abundant polymorphonuclear neutrophils, cellular debris, histiocytes, epithelioid cells, and necrosis. (c) Gömöri ×20 and (d) Gömöri ×40, revealing blastoconidia formations (arrows), morphologically consistent with Histoplasma.

(a)

(b)

(c)

(d)