Letter to the Editor
Response to “Acute Hepatitis Induced by Lyprinol, the Lipid Extract of the Green-Lipped Mussel (Perna canaliculus), in a Patient with Polyarthrosis”
Table 1
CIOMS/RUCAM score for the case report on acute hepatitis induced by Lyprinol.
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*
Explanation for variation on scale item 5—alternative nondrug causes: the RUCAM outlines two groups of nondrug causes of acute hepatitis that need to be considered which are divided into two groups. Group 1 consists of recent HAV, HBV, or HCV; biliary obstruction; alcoholism; or history of hypotension (particularly if there is underlying heart disease). Group 2 consists of complications of underlying disease and clinical or biological context for CMV, EBV, or herpes virus infection. A score of 0 is given for 5 or 4 of Group 1 being excluded and −3 given if a nondrug cause such as acute autoimmune polyarthropathy is highly probable. |