Persistent Lymphadenopathy due to IgG4-Related Disease

Table 2

Proposed comprehensive diagnostic criteria for IgG4-RD^*.

(1) Organ enlargement, mass or nodular lesions, or organ dysfunction
(2) A serum IgG4 concentration >135 mg/dL
(3) Histopathological findings of >10 IgG4 cells/high powered field and an IgG4+/IgG+ cell ratio >40%
Definite = (1), Possible = (1) + (2), Probable = (1) + (3)

^*Adapted from Umehara et al. [2].