An Uncommon Case of Pediatric Neurobrucellosis Associated with Intracranial Hypertension

Table 1

Important presenting symptoms, investigation procedures, and treatment features, comparing to other cases of neurobrucellosis presented with intracranial hypertension.

	Sinopidis et al.	Özisik et al. [4]	Yilmaz et al. [5]	Tanir et al. [6]
Patient gender and age	Male; 4 years	Female; 38 years	Female; 15 years	Female; 13 years
Clinical presentation	Vomiting; Headache; Papilledema; Horizontal diplopia	Vomiting; Diplopia; Headache; Arthralgia; Bilateral papilla stasis	Vomiting; Headache; Papilledema; Horizontal Diplopia	Intracranial hypertension, initially diagnosed as meningoencephalitis, no specific details given
Brain MRI	Normal	Normal	Normal	Normal
Blood examinations	WBC count 7.400/mL; Neutrophils 42%; Lymphocytes 48%; Normal CRP and ESR; Wright agglutination test 1: 320	WBC count 5.500/mm^3; Lymphocytes 64%, Neutrophils 24%; Monocytes 12%; ESR 20 mm/h; Brucella serum test 1/80	Normal blood count; Normal CRP; ESR 4 mm/h; Positive Rose Bengal test; Wright agglutination test 1: 160	Serum agglutination test 1: 320; 2-Mercaptoethanol test 1: 160
Opening intracranial pressure	48 mmHg	300 mm H2O	340 mm H2O	Increased, measurement not specified
CSF	162 cells/mL; Neutrophils 86%; Monocytes 14%; Glucose 32 mg/dL; Protein 60 mg/dL; Negative culture; Positive PCR reaction	Lymphocytes 80/mm^3; Protein 0.20 mg/L; Glucose 0.53 mg/L; Normal Gram and methylene blue stains; Negative ordinary culture; Positive BACTEC system culture	10 cells/μL; Glucose 58 mg/dL; Protein 48 mg/dL; Positive Rose Bengal test; Wright agglutination test 1: 80; Positive culture	500 cells/mm^3; Lymphocytes 80%; Neutrophils 20%; Glucose 47 mg/dL; Protein 58 mg/dL; Serum agglutination test 1/10; Negative culture
Treatment	Rifampicin, cotrimoxazole, ciprofloxacin added later	Doxycyclin, rifampicin, and trimethoprime with sulfamethoxazole	Streptomycin, doxycyclin, and rifampicin	Doxycyclin, rifampicin, gentamicin