Diagnostic Challenges of Tuberculous Lymphadenitis Using Polymerase Chain Reaction Analysis: A Case Study
Table 2
Outline of microbiological findings.
Three weeks after first examination
Five weeks after first examination
Nine weeks after first examination
Eleven weeks after first examination
Twelve weeks after first examination
Thirteen weeks after first examination
Sample A
The histopathological findings from an incision biopsy of a cervical lymph node revealed necrotizing granuloma
A PCR analysis of a biopsy tissue revealed a positive for MA and a negative for TB (TaqMan)
A PCR analysis of a biopsy tissue revealed a negative for MA and a positive for TB (RIT)
Sample B
A PCR analysis of an incision re-biopsy of a cervical lymph node revealed a positive for MA and a negative for TB (TaqMan)
A PCR analysis of a cultured colony revealed a negative for MA and a positive for TB (TaqMan)
A separation of viable bacteria in cultured colonies revealed no MA colonies and all TB colonies
PCR: polymerase chain reaction, MA: Mycobacterium avium, TB: Mycobacterium tuberculosis, and RIT: The Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association.