Add-On Therapy with Ertapenem in Infections with Multidrug Resistant Gram-Negative Bacteria: Pediatric Experience

Table 1

Demographic characteristics of patients and features of resistant microorganisms.

	Age	Underlying diagnosis	Clinical syndrome	Site of cultivation	Microorganism	Antibiotic sensitivity profile
						MPM/MIC	ERT/MIC	AMK/MIC	CPR/MIC	TGC/MIC
Case  1	3 moa	Infantile hemochromatosis	Bacteremia	Blood culture	Klebsiella pneumoniae	R/>6	R/>8	IR/16	R/>2	S/1
Case  2	3 yoa	Operated tetralogy of Fallot	Bacteremia	Blood culture	Klebsiella pneumoniae	R/>32	R/>32	R/>64	R/>4	R/>2
Case  3	8 moa	Primary hemophagocytic syndrome (after bone marrow transplantation)	Bacteremia	Blood culture	Klebsiella pneumoniae	R/>32	R/>32	R/>64	R/>4	S/2

MPM: meropenem; ERT: ertapenem; AMK: amikacin; TGC: tigecycline; CPR: ciprofloxacin; R: resistant; S: sensitive; IR: intermediate resistance; MIC: minimum inhibitory concentration (mg/L); yoa: years of age; moa: months of age.