A Putative Case of Methotrexate-Related Lymphoma: Clinical Course and PET/CT Findings

Figure 1

Imaging Test Results: images from 3 different PET/CT scans are shown above. Images from the patient’s initial study are on the left and show extensive abnormal areas of FDG activity on the coronal PET image and correlative CT and fused PET/CT images (inset left) of the large lesion in the liver. A second scan performed 30 days after the baseline scan shows complete resolution of the abnormal FDG activity (middle group of images) in all lesions after discontinuation of the patient’s methotrexate. No other treatment was initiated. Note persistent low attenuation lesion in the liver (inset middle). Image on the right from a repeat scan 90 days later shows multiple new lesions, most of which were not even present on the initial scan.