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Case Reports in Medicine
Volume 2012 (2012), Article ID 187039, 3 pages
Menthol Toxicity: An Unusual Cause of Coma
1Hospital Medicine/Internal Medicine Department, Peninsula Regional Medical Center, Salisbury, MD 2180, USA
2Department of Hospital Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
3Department of Pulmonary, Critical Care and Environmental Medicine, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
4Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and Department of Hospital Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, Mail Code A13, Cleveland, OH 44195, USA
Received 23 August 2012; Revised 29 October 2012; Accepted 29 October 2012
Academic Editor: Michael G. Irwin
Copyright © 2012 Motaz Baibars et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- P. Spindler and C. Madsen, “Subchronic toxicity study of peppermint oil in rats,” Toxicology Letters, vol. 62, no. 2-3, pp. 215–220, 1992.
- F. A. Andersen, “Final report on the safety assessment of Mentha Piperita (Peppermint) Oil, Mentha Piperita (Peppermint) Leaf Extract, Mentha Piperita (Peppermint) Leaf, and Mentha Piperita (Peppermint) Leaf Water,” International Journal of Toxicology, vol. 20, no. 3, supplement, pp. 61–73, 2001.
- D. L. J. Opdyke, “Monographs on fragrance raw materials,” Food and Cosmetics Toxicology, vol. 14, no. 4, pp. 307–338, 1976.
- C. Gaudioso, J. Hao, M. F. Martin-Eauclaire, M. Gabriac, and P. Delmas, “Menthol pain relief through cumulative inactivation of voltage-gated sodium channels,” Pain, vol. 153, no. 2, pp. 473–484, 2012.
- N. Hiki, M. Kaminishi, K. Yasuda et al., “Multicenter phase Ii randomized study evaluating dose-response of antiperistaltic effect of L-menthol sprayed onto the gastric mucosa for upper gastrointestinal endoscopy,” Digestive Endoscopy, vol. 24, no. 2, pp. 79–86, 2011.
- K. R. Brain, D. M. Green, P. J. Dykes, R. Marks, and T. S. Bola, “The role of menthol in skin penetration from topical formulations of ibuprofen 5% in vivo,” Skin Pharmacology and Physiology, vol. 19, no. 1, pp. 17–21, 2005.
- N. M. O'Mullane, P. Joyce, and S. V. Kamath, “Adverse CNS effects of menthol-containing olbas oil,” The Lancet, vol. 1, no. 8281, p. 1121, 1982.
- N. GM, Clinical Toxicology of Commercial Products, Williams and Wilkins, 3rd edition, 1969.
- C. A. Morton, J. Garioch, P. Todd, P. J. Lamey, and A. Forsyth, “Contact sensitivity to menthol and peppermint in patients with intra-oral symptoms,” Contact Dermatitis, vol. 32, no. 5, pp. 281–284, 1995.
- T. Umezu, “Evidence for dopamine involvement in ambulation promoted by menthone in mice,” Pharmacology Biochemistry and Behavior, vol. 91, no. 3, pp. 315–320, 2009.