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Case Reports in Medicine
Volume 2012 (2012), Article ID 267860, 4 pages
http://dx.doi.org/10.1155/2012/267860
Case Report

Contrast-Induced Neurotoxicity following Cardiac Catheterization

1Department of Neurology, SUNY Downstate Medical Center, 450 Clarkson Avenue, P.O. Box 1274, Brooklyn, NY 11203, USA
2Department of Neurology, SUNY Downstate Medical Center and Kings County Hospital Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
3Division of Neurology, Bumrungrad International Hospital, Bangkok 10110, Thailand
4Divisions of Cardiology, SUNY Downstate Medical Center and Kings County Hospital Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
5Divisions of Radiology, SUNY Downstate Medical Center and Kings County Hospital Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA

Received 21 May 2012; Revised 21 July 2012; Accepted 14 October 2012

Academic Editor: Vincenzo Di Lazzaro

Copyright © 2012 Susan Law et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We report a case of probable contrast-induced neurotoxicity that followed a technically challenging cardiac catheterization in a 69-year-old woman. The procedure had involved the administration of a large cumulative dose of an iodinated, nonionic contrast medium into the innominate artery: twelve hours following the catheterization, the patient developed a seizure followed by a left hemiplegia, and an initial computed tomography (CT) scan showed sulcal effacement in the right cerebral hemisphere due to cerebral swelling. The patient’s clinical symptoms resolved within 24 hours, and magnetic resonance imaging at 32 hours showed resolution of swelling. Contrast-induced neurotoxicity should be found in the differential diagnosis of acute neurological deficits occurring after radiological procedures involving iodinated contrast media, whether ionic or nonionic.