Burkitt Lymphoma Presenting as Unilateral Deafness in an Immunocompetent Patient

Figure 6

Karyotype (left) with arrows pointing translocation (8, 14), highlighted by FISH (dual fusion probe) study (right): the IGH gene (14q32) is in green, the MYC gene (8q24) is red, and the centromere 8 (CEP 8) is in aqua. If the patient is normal, the expected pattern would be 2 reds, 2 greens, and 2 aqua signals. The abnormal pattern is two fusions (red and green together), 1 red (normal 8), 1 green (normal 14), and 2 aqua (the two centromeres of chromosome 8).