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Case Reports in Medicine
Volume 2012 (2012), Article ID 370204, 4 pages
http://dx.doi.org/10.1155/2012/370204
Case Report

A Case Report of Spindle Cell (Sarcomatoid) Carcinoma of the Larynx

1Meharry Medical College, 1005 DR DB Todd Boulevard, Nashville, TN 37208, USA
2Department of Pathology, Meharry Medical College, 1005 DR DB Todd Boulevard, Nashville, TN 37208, USA

Received 2 October 2012; Revised 21 November 2012; Accepted 7 December 2012

Academic Editor: Gerd J. Ridder

Copyright © 2012 Harry Boamah and Billy Ballard. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Spindle cell carcinoma (SpCC) or sarcomatoid carcinoma is a highly malignant variant of squamous cell carcinoma which comprises 2% to 3% of all laryngeal cancers. It is considered to be a biphasic tumor that is composed of a squamous cell carcinoma (in situ or invasive) and spindle cell carcinoma with sarcomatous appearance. Most spindle cell tumors are polypoid and pedunculated; they are often detected at an early stage, removed by polypectomy during diagnosis, and tend to have a very good prognosis. We present a case of spindle cell carcinoma in a 67-year-old Caucasian male who presented with progressive hoarseness of his voice, dysphagia, odynophagia and a 20-pound weight loss. The patient underwent direct laryngoscopy with excision of the malignant mass and received radiation therapy. His symptoms gradually improved, and he regained good control of his voice.