Multifocal and Multicentric Glioblastoma with Leptomeningeal Gliomatosis: A Case Report and Review of the Literature

Table 1

Literature review of studies on concomitant supratentorial and infratentorial glioblastomas in adults*.

Authors and year	Case no.	Age (yrs), sex	Location		Histopathology		Treatment	Overall survival (mos)
			Supratentorial	Infratentorial	Supratentorial	Infratentorial
Present study	1	72, M	Rt posterior periventricular region	Rt cerebellar hemisphere	Glioblastoma	Glioblastoma	STR, TMZ, and WBXRT	3
Salunke et al. [34], 2010	2	50, M	Rt insula	Cerebellar vermis	Grade II astrocytoma	Glioblastoma	STR, WBXRT	18
Kotwica and Papierz, 1992 [36]	3	53, F	Lt temporal lobe	Cerebellar vermis	Glioblastoma	Pilocytic astrocytoma	GTR	10
Salvati et al. [8], 1991	4	47, M	Rt frontal lobe	Lt cerebellar hemisphere	Glioblastoma	Grade III astrocytoma	Biopsy	2
	5	42, M	Rt temporal lobe	Pons	Glioblastoma	Glioblastoma	GTR	Postoperative mortality
	6	56, F	Lt frontoparietal lobes	Rt cerebellar hemisphere	Glioblastoma	Glioblastoma	Biopsy, Chemotx, and WBXRT	7
Kudo et al. [12], 1990	7	74, M	Rt occipital lobe	Rt cerebellar hemisphere	Glioblastoma	Glioblastoma	STR	2
Bussone et al. [20], 1979	8	49, M	Rt thalamus	Rt CPA	Glioblastoma	Glioblastoma	None	4
Takeda et al. [9], 1976	9	56, M	Corpus callosum	Cerebellar vermis	Glioblastoma	Glioblastoma	Unknown	3
Ishida and Nakagawa [37], 1972	10	53, M	Rt frontal lobe	Brainstem	Glioblastoma	Glioblastoma	Unknown	18
Salles et al. [38], 1967	11	24, M	Lt temporal lobe	Lt cerebellar hemisphere	Glioblastoma	Glioblastoma	Unknown	8
Kijima et al. [39], 1962	12	31, M	Rt temporal lobe	Brainstem	Glioblastoma	Glioblastoma	Unknown	3

∗STR: subtotal resection; GTR: gross-total resection; TMZ: temozolomide; WBXRT: whole brain radiotherapy; Chemotx: chemotherapy; CPA: cerebellopontine angle.