Budd-Chiari Syndrome with Multiple Thrombi due to a Familial Arg42Ser Mutation in the Protein C Gene

Table 1

Laboratory test values of the proband upon admission.

Complete blood count
White blood cell count	6,600/μL
Red blood cell count	396 × 10^4/μL
Hemoglobin	12.4 g/dL
Hematocrit	37.6%
Platelets	16.0 × 10^4/μL
Blood biochemistry
Aspartate aminotransferase	29 IU/L
Alanine aminotransferase	46 IU/L
Alkaline phosphatase	175 IU/L
Lactate dehydrogenase	190 IU/L
γ-GTP	39 IU/L
Total bilirubin	0.8 mg/dL
Creatine phosphokinase	79 IU/L
Total cholesterol	299 mg/dL
Triglyceride	104 mg/dL
HDL-cholesterol	72 mg/dL
LDL-cholesterol	195 mg/dL
Sodium	143 mEq/L
Chloride	108 mEq/L
Potassium	3.9 mEq/L
Uric acid	3.1 mg/dL
Blood urea nitrogen	8 mg/dL
Creatinine	0.57 mg/dL
Total protein	5.1 g/dL
Albumin	3.5 g/dL
C-reactive protein	0.20 mg/dL
Hemoglobin A1c	5.6%
Thyroid-stimulating hormone	1.72 μIU/mL
Thyroxine, free (fT4)	0.8 pg/mL
Thyroxine, free (fT3)	2.0 pg/mL
BNP	21.1 pg/mL
Coagulation
APTT	32.5 s
PT-INR	1.06
D-dimer	1.40 μg/mL
Immunochemistry
Immunoglobulin G	320 mg/dL
Immunoglobulin A	71 mg/dL
Immunoglobulin M	114 mg/dL
Immunoglobulin E	17.6 IU/mL
Complement titer (CH50)	52.8 U/mL
Complement C3	111 mg/dL
Complement C4	37 mg/dL
Antinuclear antibody	<40
Lupus anticoagulant	(−)
HBs antigen	(−)
HCV-antibody	(−)
<ELISA>
MPO-ANCA	93 EU
PR3-ANCA	<10 EU
Urinalysis
pH	7.0
Specific gravity	1.010
Glucose	(−)
Protein	(−)
Cast	(−)
Erythrocytes	1–5/HPF
Leukocytes	1–5/HPF

Abbreviations: γ-GTP: gamma-glutamyl transpeptidase; HDL cholesterol: high-density lipoprotein-cholesterol; LDL cholesterol: low-density lipoprotein cholesterol; PR3-ANCA: proteinase-3 antineutrophil cytoplasmic antibody; MPO-ANCA: myeloperoxidase antineutrophil cytoplasmic antibody; APTT: activated partial thromboplastin time; BNP: B-type natriuretic peptide; PT-INR: prothrombin time-international normalized ratio.