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Case Reports in Medicine
Volume 2013 (2013), Article ID 459753, 5 pages
http://dx.doi.org/10.1155/2013/459753
Case Report

False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report

1Department of Radiation Oncology, Acibadem Adana Hospital, Acibadem University School of Medicine, Seyhan, 01130 Adana, Turkey
2Department of Nuclear Medicine, Acibadem Adana Hospital, Seyhan, 01130 Adana, Turkey
3Department of Internal Medicine, Acibadem Adana Hospital, Acibadem University School of Medicine, Seyhan, 01130 Adana, Turkey
4Department of Thoracic Surgery, Inonu University School of Medicine, 44000 Malatya, Turkey

Received 20 December 2012; Accepted 11 February 2013

Academic Editor: Bruno Megarbane

Copyright © 2013 Gamze Uğurluer et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Breast cancer is the most frequently diagnosed cancer among females. It is accepted that lymph node involvement with metastatic tumor and the presence of distant metastasis are the most important prognostic factors. Accurate staging is important in determining prognosis and appropriate treatment. Positron emission tomography with computed tomography detects malignancies using 2-[18F]-fluoro-2-deoxy-d-glucose (18F-FDG PET CT) with high accuracy and they contribute to decisions regarding diagnosis, staging, recurrence, and treatment response. Here, we report a case of false positive metastatic mediastinal lymph nodes that were diagnosed by 18F-FDG PET CT in a 40-year-old breast cancer patient who had undergone preoperative evaluation. Right paratracheal, prevascular, aorticopulmonary, precarinal, subcarinal, hilar, and subhilar multiple conglomerated mediastinal lymph nodes were revealed in addition to left breast mass and axillary lymph nodes. Mediastinoscopy was performed with biopsy and pathology was reported as granulomatous lymphadenitis. In conclusion, any abnormal FDG accumulation in unusual lymph nodes must be evaluated carefully and confirmed histopathologically.