Case Report

The Occurrence or Fibrillary Glomerulonephritis in Patients with Diabetes Mellitus May Not Be Coincidental: A Report of Four Cases

Table 1

Clinical, biochemical, and histologic data from patients with fibrillary glomerulonephritis.

No.Sex Age SCrProteinuria HaematuriaTChLDLTGCUaLMSGIFEM (fibrils)DMIS

1M551.0213.52Yes 319491654.21 MG1/14IgG, C, and κ15–20 nmYes Yes
2F480.934.58Yes 1781176.35MG7/18IgG, IgM, λ, and C17 nmYes No
3M451.859.33No2285146.21 MP3/15IgG, κ, and λ18.22 nmYes No
4M551.542.66194108405.2GSF4/11IgG, λ, and C21–25 nmYes No

SCr: serum creatinine at diagnosis in mg/dL; Proteinuria: urine protein at diagnosis in g/day; Haematuria: microhematuria; TCh: total cholesterol; LDL: LDL cholesterol; TGC: triglycerides; Ua: uric acid; LM: light microscopy; SG: sclerotic glomeruli; EM: electron microscopy; IF: immunofluorescence; DM: diabetes mellitus; IS: immunosuppressive treatment; MG: membranous glomerulonephritis; MP: membranoproliferative glomerulonephritis; EFG: focal and segmental glomerulosclerosis.