Case Report

Pulmonary Phaeohyphomycosis Caused by Phaeoacremonium in a Kidney Transplant Recipient: Successful Treatment with Posaconazole

Table 1

Skin and subcutaneous infection, osteomyelitis, endophthalmitis, and onychomycosis due to Phaeoacremonium species.

Number ReferenceSpeciesAge/sexUnderlying conditionClinical diseaseTreatmentOutcome

1Padhye et al., 1998 [4]P. inflatipes 83/FNoneSubcutaneous infection of the footExcisionComplete healing
2Matsui et al., 1999 [5]P. rubrigenum 61/FRheumatoid arthritisSubcutaneous mass of the footExcision
Itraconazole
Fluconazole
Recurred
3Kitamura et al., 2000 [6]P. parasiticum 59/FNoneSubcutaneous nodule below the kneeExcisionComplete healing
4Guarro et al., 2003 [7]P. aleophilum 19/MNoneFistulized nodule on the ankleExcision (six times)
Itraconazole
Cured
5Guarro et al., 2003 [7]P. rubrigenum 55/MRenal transplantMultiple nodules of ankle and footExcision
Itraconazole
Terbinafine
Fluconazole
Not resolved
6Llinas et al., 2005 [8]Phaeoacremonium species54/FMyelodysplastic syndrome, IgA deficiencyOlecranon bursitisExcision
Itraconazole
Resolved
7Baddley et al., 2006.[9]P. parasiticum 40/MCardiac transplantMultiple skin lesionsAmphotericin B, Itraconazole
Debridement
Died
8Hemashettar et al., 2006 [10]P. krajdenii 41/MNoneMycetomaItraconazole
Debridement
Recurred
9Marques et al., 2006 [11]P. parasiticum 49/MRenal transplantDraining cystic tumors on the footItraconazole
Amphotericin B
Improved
10Huynh et al., 2007 [12]P. parasiticum 19/MPenetrating globe injuryEndophthalmitisAmphotericin B
Voriconazole
Improved
11Farina et al., 2007 [13]P. parasiticum 41/MKidney transplantSubcutaneous nodule on the forefingerExcisionResolved
12Baradkar et al., 2009 [14]P. parasiticum 26/FNoneSubcutaneous abscess on the forearmDebridement Amphotericin B ItraconazoleResolved
13Sun et al., 2011 [15]P. parasiticum 55/MNoneOnychomycosisDiseased nail was trimmed off
Topical sulconazole
Cured
14Aguilar et al., 2011.[16]P. parasiticum 52/FType 2 diabetes hypothyroidism.EumycetomaSurgery (multiple times), ItraconazoleImproved
15Baradkar et al., 2011 [17]P. infalitipes 30/MNoneSubcutaneous mass of the footDebridement, Amphotericin B, ItraconazoleCured
16Choi et al., 2011 [18]Phaeoacremonium species54/MRenal transplantSubcutaneous mass on the third fingerExcisionResolved
17Mazzurco et al., 2012 [19]Phaeoacremonium species74/MRheumatoid arthritis, on infliximabNodule on the legExcision
Itraconazole
Resolved
18Furudate et al., 2012 [20]P. rubrigenum 76/FStill's disease, on prednisoloneSubcutaneous nodules on the legDebridement, ItraconazoleResolved
19To et al., 2012 [21]P. parasiticum 69/MDiabetes mellitusRight knee Pain and swellingArthrotomy and drainage, Itraconazole, total knee replacementImproved
20Guarro et al., 2006 [22]P. venezuelense 28/MChronic myeloid leukemiaSubcutaneous mycosesSurgical excisionNot known