Serum Cytokine Profile in a Patient Diagnosed with Dysferlinopathy

Table 2

Analysis of patient and controls cytokine profile.

Analyte	Control ()	Patient
Immunoregulatory
IL-1b	19.6 ± 4.9	18.1
IL-1RA	376.2 ± 162.7	291.7
IL-2	129 ± 17.9	78
IL-4	78.8 ± 5.0	87
IL-5	1.5 ± 0.3	0.7 ± 0.5
IL-6	67.3 ± 21.0	46.9
IL-7	2.5 ± 1.3	3.5 ± 1.5
IL-9	80.4 ± 9.9	89
IL-12 (p70)	31.1 ± 1.0	23
IL-10	31.7 ± 3.7	95
IL-13	59.3 ± 5.4	35
IL-15	131.3 ± 34.3	160.1
IL-17	3826.8 ± 367.7	5483
CCL11	4314.4 ± 1320.2	1984
IFN-γ	2960.3 ± 468.7	2391
Leukocyte chemoattractants
CCL2	444.9 ± 132.9	926.2
CCL3	23.3 ± 2.4	18
CCL4	615.2 ± 147.8	453.4
CCL5	40267.4 ± 1767.8	60422.1
CXCL10	7446.1 ± 1865.6	9446.9
G-CSF	111.9 ± 20.1	202.9
GM-CSF	80.7 ± 22.8	56
IL-8	370.6 ± 170.7	37.3
TNF-α	229.2 ± 22.6	210
Angiogenesis
VEGF	2367.1 ± 705.7	856
PDGF-BB	34535.4 ± 2952.9	39325.6
bFGF	2.4 ± 1.4	1.8 ± 0.9

Values differ considerably from that in the control.