Ten-Year Follow-Up of Collision Tumors Composed of Craniopharyngioma and Pituitary Adenoma: A Case Report and Literature Review

Table 1

Literature review for the collision tumors composed of CP and PA.

Case no., author, year	Age, sex	Initial symptom	Initial diagnosis	Hormone	1^st treatment	2^nd treatment	Pathology of PA	Pathology of CP	Positional relation for CP and PA	Follow-up duration/prognosis after surgery
1, Prabhakar et al., 1971 [1]	29, M	Acromegaly, headache, visual disturbance	PA	GH	Craniotomy	None	GH producing	Adamantinomatous	Separate	4 days/dead due to diabetes insipidus
2, Shishikina et al., 1981 [2]	57, M	Headache, double vision, visual disturbance	CP	PRL (5908 mU/ml)	Craniotomy	Craniotomy	PRL producing	Adamantinomatous	Separate	10 days/dead due to panhypopituitarism
3, Wheatley et al., 1986 [3]	61, M	Headache, visual disturbance, reduced libido	CP	PRL (8180 mU/ml)	Craniotomy	VP shunt	PRL producing	Adamantinomatous	Separate	2 months/dead due to sudden cardiac arrest
4, Dong et al., 1986 [4]	32, F	Acromegaly, amenorrhea, lactation	PA	GH; PRL	Transsphenoidal	Craniotomy	GH/PRL producing	Adamantinomatous	Separate	n.d./n.d.
5, Asari et al., 1987 [5]	47, M	Visual disturbance	PA	PRL (360 ng/ml)	Transsphenoidal	Craniotomy (3^rd craniotomy)	PRL producing	Adamantinomatous	Separate	11 months/good
6, Jiang and Cheng, 1987 [6]	36, M	Visual disturbance	PA	Nonfunctioning	Transsphenoidal	Craniotomy	Nonfunctioning	Adamantinomatous	Separate	n.d./n.d.
7, Cusimano et al., 1988 [7]	62, F	Personality change, visual disturbance	CP	PRL (34 ng/ml)	Craniotomy (after VP shunt)	Craniotomy	PRL producing (micro)	Adamantinomatous	Separate	14 months/dead due to pulmonary embolism
8, Yoshida et al., 2008 [8]	29, M	Atrial fibrillation	PA	TSH	Transsphenoidal	None	TSH producing	Adamantinomatous	Encase	n.d./n.d.
9, Karavitaki et al., 2008 [9]	50, M	Headache, insomnia, reduced libido	PA	LH, FSH	Transsphenoidal	None	LH/FSH producing	Adamantinomatous	Encase	4 years/good (no recurrence)
10, Sargis et al., 2009 [10]	59, M	Visual disturbance	PA	LH, FSH	Craniotomy	None	LH/FSH producing	Adamantinomatous	Encase	n.d./diabetes insipidus
11, Moshkin et al., 2009 [11]	12, M	Partial hypopituitarism	CP	Nonfunctioning	Craniotomy	None	Nonfunctioning	Adamantinomatous	Encase	n.d./n.d.
12, Gokden and Mrak, 2009 [12]	47, M	Visual disturbance, headache	PA	Nonfunctioning	Transsphenoidal	None	Nonfunctioning	Adamantinomatous	Encase	1 year/good (no recurrence)
13, Jin et al., 2013 [13]	47, F	Visual disturbance, headache	PA	PRL (111 ng/ml); ACTH (116 pg/ml)	Transsphenoidal	Craniotomy	Nonfunctioning	Adamantinomatous	Separate	3 months/good (no recurrence)
14, Finzi et al., 2014 [14]	75, F	Diplopia	PA	PRL (54 ng/ml)	Transsphenoidal	None	Nonfunctioning	Adamantinomatous	Encase	10 months/good (no recurrence)
15, present case	48, M	Memory disturbance	CP	Nonfunctioning	Craniotomy	Transsphenoidal	Nonfunctioning	Adamantinomatous	Separate	10 years/good (no recurrence)

CP, craniopharyngioma; PA, pituitary adenoma; GH, growth hormone; PRL, prolactin; TSH, thyroid-stimulating hormone; LH, luteinizing hormone; FSH, follicle-stimulating hormone; ACTH, adrenocorticotropic hormone; VP, ventriculoperitoneal; author’s surmise based on reference; n.d., not described.