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Case Reports in Nephrology
Volume 2012 (2012), Article ID 132085, 4 pages
http://dx.doi.org/10.1155/2012/132085
Case Report

Crescentic Glomerulonephritis with Anti-GBM and p-ANCA Antibodies

Department of Medicine, Bakersfield Memorial Hospital, Bakersfield, CA 93301, USA

Received 10 January 2012; Accepted 1 February 2012

Academic Editors: C. Garcia and H. Schiffl

Copyright © 2012 Tariq Javed and Parag Vohra. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We are presenting a case of renal failure with anti-GBM and p-ANCA antibodies positive. Patients with dual antibodies are considered to be a vasculitis-variant of anti-GBM antibody nephritis. These patients may have atypical presentation and it may delay diagnosis and treatment. Recurrence rate is higher in these patients. We reviewed the literature of cases and studies on cresenteric glomerulonephritis with anti-GBM and p-ANCA positive patients. We recommend that patients suspected with pulmonary-renal syndrome should be checked for anti-GBM and p-ANCA antibodies, should undergo renal biopsy and should should have close long term follow up to watch for recurrence.