Corticosteroids in Patients with IgA Nephropathy and Severe Chronic Renal Damage

Table 1

Baseline clinical and histological characteristics of the four patients.

Patient	IE	RM	CS	LA
Age (years)	55	54	46	42
Body mass index (kg/m^2)	31	26	28	27
Systolic BP (mmHg)	162	155	130	123
Diastolic BP (mmHg)	92	90	80	80
Serum creatinine (mg/dL)	3.0	3.5	3.9	3.2
Proteinuria (g/day)	5.1	3.4	4.0	1.8
eGFR (using MDRD)	26.2	19.5	17.8	22.7
Treatment with ACEI	No	Yes	Yes	No
Treatment with ARB	Yes	No	No	Yes
Glomeruli with global sclerosis	50%	50%	43%	33%
Tubular atrophy	25–50%	>50%	>50%	25–50%
Interstitial fibrosis	Moderate	Severe	Severe	Moderate
Arterial sclerosis	Severe	Severe	Not Eval.	Moderate