Case Report

Levamisole/Cocaine Induced Systemic Vasculitis and Immune Complex Glomerulonephritis

Table 1

Lab results.

VariableResult on admission (reference range)Result at discharge (reference range)

White cell count 12.7 (3.5–10.1)5.7 (3.5–10.1)
Neutrophils %10.8 (1.6–7.2)4.6 (1.6–7.2)
Lymphocytes %1.4 (1.1–4.0)0.8 (1.1–4.0)
Eosinophils %0.1 (0.0–0.4)0.0 (0.0–0.4)
Basophils %0.1 (0.0–0.1)0.0 (0.0–0.1)
Monocytes %0.3 (0.0–0.9)0.3 (0.0–0.9)
Hemoglobin, g/dL 6.1 (13.5–17.0)9.4 (13.5–17.0)
Platelet count 334 (150–400)267 (150–400)
Sodium mmol/L120 (135–145)138 (135–145)
Potassium mmol/L6.9 (3.5–5.2)4.6 (3.5–5.2)
Chloride mmol/L87 (95–107)100 (95–107)
Carbon dioxide mmol/L10 (21–31)24 (21–31)
Blood urea nitrogen mg/dL 195 (8–22)67 (8–22)
Creatinine mg/dL20.83 (0.60–1.40)6.77 (0.60–1.40)
Calcium mg/dL5.6 (8.5–10.5)8.6 (8.5–10.5)
Phosphorus mg/dL20.2 (2.3–4.3)5.8 (2.3–4.3)
Aspartate aminotransferase, U/L721 (10–37)39 (10–37)
Alanine aminotransferase, U/L 252 (9–47)62 (9–47)
Alkaline phosphatase, U/L146 (30–110)113 (30–110)
Total bilirubin, mg/dL0.8 (0.3–1.2)0.3 (0.3–1.2)
Albumin, g/dL2.9 (3.5–5.1)3.4 (3.5–5.1)
Protein, g/dL5.3 (6.4–8.6)5.3 (6.4–8.6)
International normalized ratio1.71.1
Partial thromboplastin time, sec44.1 (25.0–32.0)28.8 (25.0–32.0)
Urine protein/creatinine ratio4.7 (0.0–0.2)
Urinalysis 3+ protein, 2+ blood, 10–20 RBC, and Hyaline and RBC cast
ESR, mm/hr 61 (0–20)
CRP mg/dL7.4 (0.0–1.0)
Complement C3, mg/dL42 (70–176)
Complement C4, mg/dL7.7 (12.1–42.9)
Anti-nuclear antibodies, IU/mL<1 : 160 (<1 : 160)Negative (<1 : 160)
Anti-double-stranded DNA, IU/mL 6.6 (0.0–29.9)
Anti-neutrophil cytoplasmic antibody1 : 640 p-ANCA (<1 : 20)
Anti-SSA, U0.9 (<20)
Myeloperoxidase antibody, U2.8 (<0.4)
Proteinase-3 auto antibody, U 0.4 (<0.4)
Cryoglobulin screen Negative
Lupus anticoagulantNegative
Serum and protein electrophoresisNegative for monoclonal antibodies
Tuberculin skin test Negative
HIV-1 and HIV-2 antibodiesNegative
Acute hepatitis panel Negative for hepatitis B and hepatitis C
Rapid plasma reagin Negative
Histoplasma urine antigen Negative
Blood and urine culturesNegative

No serum creatinine values were available prior to admission.